반응 #305069

반응 방정식

ethyl 3-(4-pyrimidinyl)-3-oxopropionate

ethyl 3-(pyridin-4-yl)-3-oxopropionate

2-(2-iminoazepan-3-yl)-1H-isoindole-1,3(2H)-dione hydrochloride

→

(+/−)2-(4-oxo-2-pyrimidin-4-yl-4,6,7,8,9,10-hexahydropyrimido[1,2-a]azepin-10-yl)-1H-isoindole-1,3(2H)-dione

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후처리

1. 1
   기타prepared by analogy to the method
2. 2
   기타the compound was obtained as a white powder

실험 절차

By analogy with the method described in example 1 (step 1.3), using ethyl 3-(4-pyrimidinyl)-3-oxopropionate (prepared by analogy to the method described in patent DE 2705582) in place of ethyl 3-(pyridin-4-yl)-3-oxopropionate and using 2-(2-iminoazepan-3-yl)-1H-isoindole-1,3(2H)-dione hydrochloride (1:1), the compound was obtained as a white powder.

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