반응 #3028

반응 방정식

hydrochloric acid

2,4-dinitrophenol

octadecyl bromide

sodium carbonate

→

1-octadecyloxy-2,4-dinitrobenzene

수율 79.1%

용매

dimethylformamide

water

반응 조건

후처리

1. 1
   추출extracted with ether
2. 2
   세척The extracts were washed with water and brine
3. 3
   건조dried over magnesium sulfate
4. 4
   기타The solvent was removed
5. 5
   기타the solid recrystallized

실험 절차

A mixture of 2,4-dinitrophenol (85 wt %, 6.72 g, 31 mmol), octadecyl bromide (20.7 g, 62 mmol), sodium carbonate (6.57 g, 62 mmol) and dimethylformamide (31 mL) was heated to 100° C. under a nitrogen atmosphere for 22 h. The cooled mixture was diluted with water (200 mL), acidified with 10N hydrochloric acid (50 mL) and extracted with ether. The extracts were washed with water and brine, and dried over magnesium sulfate. The solvent was removed and the solid recrystallized to give 1-octadecyloxy-2,4-dinitrobenzene (10.7 g, 79%): mp 63.5°-64.0° C.

출처