반응 #2984

반응 방정식

KCN

3-(7-methoxy-1-naphthyl)propyl mesylate

3-(7-METHOXY-1-NAPHTHYL)PROPYL MESYLATE

→

4-(7-METHOXY-1-NAPHTHYL)BUTYRONITRILE

용매

DMSO

반응 조건

후처리

1. 1
   온도to reflux for 2 h
2. 2
   온도to cool
3. 3
   추출The resulting mixture is extracted with ether
4. 4
   세척The organic phase is washed with water
5. 5
   건조dried over CaCl2
6. 6
   기타evaporated
7. 7
   기타The product obtained
8. 8
   기타is recrystallized

실험 절차

In a 100-cm3 flask, the 3-(7-methoxy-1-naphthyl)propyl mesylate obtained in stage D is dissolved in DMSO. KCN is added and the mixture is brought to reflux for 2 h. It is allowed to cool. It is poured into a water/ice mixture. The resulting mixture is extracted with ether. The organic phase is washed with water, dried over CaCl2 and evaporated. The product obtained is recrystallized.

출처