반응 #2980

반응 방정식

hydride

lithium aluminum hydride

methyl (7-methoxy-1-naphthyl)acetate

water

→

2-(7-METHOXY-1-NAPHTHYL)ETHANOL

용매

ether

ether

반응 조건

후처리

1. 1
   workup.ADDITIONare added slowly
2. 2
   workup.WAITThe reaction medium is left
3. 3
   workup.STIRRINGstirring for 30 minutes
4. 4
   여과The reaction medium is filtered
5. 5
   추출The aqueous phase is extracted with 3 times 50 cm3 of ether
6. 6
   건조the ether phases are dried over magnesium sulfate
7. 7
   기타evaporated
8. 8
   기타The white solid obtained
9. 9
   기타is recrystallized

실험 절차

3.34 g of lithium aluminum hydride are placed in a 250-cm3 flask, and ether is added gently with stirring. Using a dropping funnel, 5 g of methyl (7-methoxy-1-naphthyl)acetate previously dissolved in 50 cm3 of ether are added slowly. The reaction medium is left stirring for 30 minutes. It is poured very slowly into a mixture of water and ice so as to hydrolyze the excess unreacted hydride. The reaction medium is filtered. The aqueous phase is extracted with 3 times 50 cm3 of ether, and the ether phases are dried over magnesium sulfate and evaporated. The white solid obtained is recrystallized.

출처