반응 #2837

반응 방정식

(-)-(R)-2-methoxypropanol

p-toluenesulphonic acid chloride

→

(+)-(R)-2-methoxypropyl-p-toluenesulphonate

용매

pyridine

반응 조건

실험 절차

By reacting (-)-(R)-2-methoxypropanol with p-toluenesulphonic acid chloride in pyridine analogously to R. S. Tipson [J. Org. Chem. 9 (1944) 235] the (+)-(R)-2-methoxypropyl-p-toluenesulphonate is obtained in the form of a yellowish oil with a specific rotation of [α]D25 =+3.7° (c=100) and analogously, from (+)-(S)-2-methoxy-propanol, the corresponding (-)-(S)-2-methoxypropyl-p-toluenesulphonate is obtained with a rotation of [α]D25 =-3.7° (c=100).

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