반응 #2827

반응 방정식

4-amino-3-nitrobenzoic acid

1-hydroxybenzotriazole

dicyclohexylcarbodiimide

morpholine

→

solid

4-amino-3-nitrobenzoic acid morpholide

용매

N,N-dimethylformamide

반응 조건

후처리

1. 1
   여과The insolubles were filtered out
2. 2
   세척washed with N,N-dimethylformamide
3. 3
   농축concentrated

실험 절차

A mixture of 4-amino-3-nitrobenzoic acid (7.40 g), 1-hydroxybenzotriazole (6.59 g), dicyclohexylcarbodiimide (10.90 g), dry N,N-dimethylformamide (74 ml), and morpholine (4.3 ml) was stirred at room temperature for 2 hours. The insolubles were filtered out, and washed with N,N-dimethylformamide. The filtrate and the washing were combined, and concentrated to obtain a yellowish brown solid (16.01 g).

출처