반응 #2805

반응 방정식

1-chloromethyl-2-vinyl-benzene

sodium iodide

water

→

title compound

수율 95.0%

1-Iodomethyl-2-vinyl-benzene

수율 95.0%

용매

acetone

반응 조건

후처리

1. 1
   온도Heat
2. 2
   온도at gentle reflux for 30 minutes
3. 3
   온도Cool
4. 4
   추출extract with pentane (200 mL)
5. 5
   건조Dry (MgSO4)
6. 6
   기타evaporate the solvent in vacuo

실험 절차

Dissolve 1-chloromethyl-2-vinyl-benzene (4.0 g, 26 mmol) in acetone (100 mL) and add sodium iodide (4.5 g, 30 mmol). Heat at gentle reflux for 30 minutes. Cool, add water (150 mL) and extract with pentane (200 mL). Dry (MgSO4) and evaporate the solvent in vacuo to give the title compound (95%).

출처