반응 #2767

반응 방정식

trifluoroacetic acid ethyl ester

1,4,7-triazaheptane

→

1,7-Bis(trifluoroacetyl)-1,4,7-triazaheptane

용매

tetrahydrofuran

반응 조건

후처리

1. 1
   농축concentrated by evaporation in a vacuum
2. 2
   기타The remaining oil is crystallized from hexane

실험 절차

113.3 g (790 mmol) of trifluoroacetic acid ethyl ester is instilled in a solution of 41.14 g (390 mmol) of 1,4,7-triazaheptane in 350 ml of tetrahydrofuran at 0° C. and under nitrogen. It is allowed to stir overnight at room temperature, concentrated by evaporation in a vacuum. The remaining oil is crystallized from hexane.

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