반응 #2507831

반응 방정식

7-bromomethyl-6-fluoro-3-pentylchroman

triphenylphosphine

→

(6-Fluoro-3-pentylchroman-7-ylmethyl)triphenylphosphonium bromide

용매

acetonitrile

반응 조건

후처리

1. 1
   온도The batch is subsequently cooled to 0° C.
2. 2
   여과the precipitated (6-fluoro-3-pentylchroman-7-ylmethyl)triphenylphosphonium bromide is filtered off with suction
3. 3
   기타dried in vacuo

실험 절차

11.0 g (34.9 mmol) of 7-bromomethyl-6-fluoro-3-pentylchroman and 9.20 g (35.1 mmol) of triphenylphosphine are dissolved in 70 ml of acetonitrile, and the mixture is stirred overnight at room temp. The batch is subsequently cooled to 0° C., and the precipitated (6-fluoro-3-pentylchroman-7-ylmethyl)triphenylphosphonium bromide is filtered off with suction and dried in vacuo.

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