반응 #2498549

반응 방정식

methyl 4-bromo-2-(1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoate

1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine

→

title compound

수율 63.1%

[4-bromo-2-(1,1-dioxo-1λ6-isothiazolidin-2-yl)phenyl][4-(5-cyclopropyl-3-methylpyridin-2-yl)piperazin-1-yl]methanone

수율 63.1%

반응 조건

후처리

1. 1
   기타described in Preparation Example 83 and by the reaction and treatment in the same manner as in Preparation Example 166

실험 절차

Using methyl 4-bromo-2-(1,1-dioxo-1λ6-isothiazolidin-2-yl)benzoate (1 g) described in Preparation Example 239 and 1-(5-cyclopropyl-3-methylpyridin-2-yl)piperazine (0.65 g) described in Preparation Example 83 and by the reaction and treatment in the same manner as in Preparation Example 166, the title compound (0.98 g) was obtained.

출처