반응 #2469356

반응 방정식

diethylether

3-bromophenol

potassium carbonate

→

1-bromo-3-cyclopropoxybenzene

용매

water

DMF

반응 조건

후처리

1. 1
   기타The organic layer was separated
2. 2
   세척washed with water, brine
3. 3
   건조dried over Na2SO4
4. 4
   여과filtered
5. 5
   기타evaporated
6. 6
   기타An oil was obtained

실험 절차

A mixture of 3-bromophenol (2.4 g, 13.9 mmol), bomocyclopropane (6.66 ml, 83 mmol) and potassium carbonate (9.6 g, 69.5 mmol) in DMF (16 ml) was heated at 180° C. in a microwave oven for 8 hours. The reaction mixture was diluted with a mixture of diethylether and water. The organic layer was separated, washed with water, brine, dried over Na2SO4, filtered and evaporated. An oil was obtained, 2.87 g, with a purity of 81%.

출처