반응 #2468004

반응 방정식

2-(1-trityl-1H-imidazol-4-yl)-propionitrile

→

2-(1-trityl-1H-imidazol-4-yl)-propylamine

용매

ammonia

반응 조건

후처리

1. 1
   여과4 bar H2 pressure the catalyst is filtered off
2. 2
   기타This crude product is used in the following reaction step without further purification

실험 절차

3.2 g 2-(1-trityl-1H-imidazol-4-yl)-propionitrile are dissolved in 150 mL methanolic ammonia (7 mol/L) and Raney nickel is added. After 12 h and 4 bar H2 pressure the catalyst is filtered off and the solvent is eliminated in vacuo. This crude product is used in the following reaction step without further purification.

출처