반응 #2449652

반응 방정식

4-aminopyridine

lactyl acetate

carbodiimide

→

lactyl-4-aminopyridine

용매

water

반응 조건

후처리

1. 1
   기타The resulting lactyl-4-aminopyridine is collected as an oil
2. 2
   기타purified to pharmaceutical purity

실험 절차

A mixture of 4-aminopyridine (5 mmol) and lactyl acetate (5 mmol) is added to 0.1M carbodiimide [N-cyclohexyl-N′-2-(4-methyl-morpholinium) ethyl carbodiimide-p-toluene sulphonate or CMC] in distilled water adjusted to pH 4.5, such that the final volume is 200 ml. The reaction is performed for 24 hours at 4° C. The resulting lactyl-4-aminopyridine is collected as an oil and purified to pharmaceutical purity.

출처