반응 #2446123

ord-03866808fd904a1ca9179c06a7e440cf

반응 방정식

Cl.Oc1ccc(CCl)c2cccnc12
5-chloromethyl-8-hydroxyquinolinoline
Cl.Oc1ccc(CCl)c2cccnc12
5-chloromethyl-8-hydroxyquinoline hydrochloride
C#CCN1CCNCC1
N-propargyl piperazine
→
C#CCN1CCN(Cc2ccc(O)c3ncccc23)CC1
title compound
C#CCN1CCN(Cc2ccc(O)c3ncccc23)CC1
5-(4-propargylpiperazin-1-ylmethyl)-8-hydroxy-quinoline

반응물

Cl.Oc1ccc(CCl)c2cccnc12
5-chloromethyl-8-hydroxyquinolinoline
Cl.Oc1ccc(CCl)c2cccnc12
5-chloromethyl-8-hydroxyquinoline hydrochloride
C#CCN1CCNCC1
N-propargyl piperazine

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The title compound was prepared by reaction of 5-chloromethyl-8-hydroxyquinolinoline (A2) with N-propargyl piperazine as follows:

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US08685955B2uspto-grants-2014_04