반응 #2383773

반응 방정식

1,2-bis(bromomethyl)naphthalene

N-bromosuccinimide

2,2′-azobis(isobutyronitrile)

→

1-(bromomethyl)-2-(dibromomethyl)naphthalene

수율 64.0%

용매

carbon tetrachloride

반응 조건

후처리

1. 1
   여과the reaction mixture was filtered
2. 2
   세척the residue was washed with 150 ml of dichloromethane
3. 3
   workup.ADDITIONThe combined solution was treated by the column chromatography (silica gel/dichloromethane) without additional treatments and 16 g (the yield: 64%) of a white solid of 1-(bromomethyl)-2-(dibromomethyl)naphthalene
4. 4
   기타was obtained

실험 절차

In 150 ml of carbon tetrachloride, 20 g (64 mmole) of 1,2-bis(bromomethyl)naphthalene and 23 g (130 mmole) of N-bromosuccinimide were suspended. To the obtained suspension, 1.1 g (6.7 mmole) of 2,2′-azobis(isobutyronitrile) was added and the mixture was vigorously stirred at 100° C. for 2 hours. After the reaction was completed, the reaction mixture was filtered and the residue was washed with 150 ml of dichloromethane. The filtrate and the washing were combined. The combined solution was treated by the column chromatography (silica gel/dichloromethane) without additional treatments and 16 g (the yield: 64%) of a white solid of 1-(bromomethyl)-2-(dibromomethyl)naphthalene was obtained.

출처