반응 #2374825

반응 방정식

2-(2'-hydroxy-5'-methacryloyloxypropylphenyl)-2H-benzotriazole

sodium methylate methanol

→

6-(2H-benzotriazol-2-yl)-4-methacryloyloxypropyl-2-[3'-(2H-benzotriazol-2-yl)-2'-hydroxy-5'-methylphenyl]methylphenol

수율 71.0%

용매

xylene

반응 조건

후처리

1. 1
   온도The mixture was then refluxed in a nitrogen stream for 10 hours
2. 2
   기타After the completion of the reaction
3. 3
   기타Yellow crystals precipitated at this point
4. 4
   기타were separated through filtration
5. 5
   기타recrystallized from chloroform

실험 절차

Ten grams (30.9 mmols) of crude 2-(3'-N,N-diethylaminomethyl-2'-hydroxy-5'-methylphenyl)-2H-benzotriazole obtained following the procedures of Synthesis Example 1 and 10.5 g (31.1 mmols) of 2-(2'-hydroxy-5'-methacryloyloxypropylphenyl)-2H-benzotriazole were dissolved in 64 ml of xylene, and 1.5 ml of a 28% sodium methylate-methanol solution were added thereto. The mixture was then refluxed in a nitrogen stream for 10 hours. After the completion of the reaction, the reaction mixture was cooled to room temperature. Yellow crystals precipitated at this point were separated through filtration, and recrystallized from chloroform to obtain 12.8 g of 6-(2H-benzotriazol-2-yl)-4-methacryloyloxypropyl-2-[3'-(2H-benzotriazol-2-yl)-2'-hydroxy-5'-methylphenyl]methylphenol (hereinafter abbreviated as "RUVA-3") as white crystals (yield 71.0%, purity 98.6%).

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