반응 #2358519

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( 2 )

N-{2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl}-N-propylamine

1-(2-bromoethoxy)-3-fluoro-5-methylsulfonyl-benzene

aminomethylcyclopropane

→

N-(cyclopropylmethyl)-N-{2-[3-fluoro-5-(methylsulfonyl)-phenoxy]ethyl}amine

용매

ethanol

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후처리

1. 1
   기타Preparation

실험 절차

Preparation according to Example 1 but performed in one portion: 1-(2-bromoethoxy)-3-fluoro-5-methylsulfonyl-benzene (0.05 g, 0.16 mmol) and aminomethylcyclopropane (0.11 ml, 1.3 mmol) in ethanol (5 ml). MS m/z (relative intensity, 70 eV) 287 (M+, 2), 246 (6), 138 (2), 84 (bp), 56 (14).

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