반응 #2314289

반응 방정식

1-(4′-(2-tetrahydropyranyloxy)phenyl)-3-bromopropane

triphenylphosphine

→

[3-(4-[2-Tetrahydropyranyloxy]phenyl)propyl]triphenylphosphonium bromide

용매

dimethylformamide

반응 조건

후처리

1. 1
   온도The reaction mixture is then cooled to room temperature
2. 2
   여과The white precipitate is filtered
3. 3
   세척washed with ethyl acetate
4. 4
   기타dried under vacuum

실험 절차

To a solution of 1-(4′-(2-tetrahydropyranyloxy)phenyl)-3-bromopropane 3C (4.2 g) in anhydrous dimethylformamide (11.3 mL) is added triphenylphosphine (6.12 g). The reaction mixture is stirred under nitrogen at 100° C. overnight. The reaction mixture is then cooled to room temperature. The white precipitate is filtered and washed with ethyl acetate, then dried under vacuum.

출처