반응 #2304306

ord-8f85489456cb4e29b1deaff29b40e3a0

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시약

없음

반응 조건

상세 조건

See reaction.notes.procedure_details.

후처리

1
기타was administered by mouth at t=0 minutes
2
기타was discontinued at t=120 minutes

실험 절차

At t=30, vehicle, or amylin ±AC-0253 was begun. Amylin dose rates were 50, 100 and 300 pmol/kg/min. Dose rates of AC-0253 were 500 and 1500 pmol/kg/min. 25% glucose (1 gm/kg) was administered by mouth at t=0 minutes. Amylin ±AC-0253 was discontinued at t=120 minutes. Samples for insulin, glucose and lactate were obtained at 15 minutes intervals from t=−45 to t=180 minutes. Samples for rat amylin and AC-0253 were taken at t=60 and 120 minutes.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07407934B2uspto-grants-2008_08