반응 #2298628

반응 방정식

(6-(3-thienyl)thieno[3,2-d]pyrimidin-4-yl)hydrazine hydrochloride

(6-(3-Thienyl)thieno[3,2-d]pyrimidin-4-yl)hydrazine hydrochloride

3-pyridinecarboxaldehyde

→

3-pyridinecarboxaldehyde(6-(3-thienyl)thieno[3,2-d]pyrimidin-4-yl)hydrazone

수율 87.0%

용매

ethanol

반응 조건

후처리

1. 1
   온도was heated
2. 2
   온도at reflux for 4 hours
3. 3
   여과the solid product was collected by vacuum filtration

실험 절차

A suspension of (6-(3-thienyl)thieno[3,2-d]pyrimidin-4-yl)hydrazine hydrochloride (222, 39 mg, 0.14 mmol) and 3-pyridinecarboxaldehyde (20 mg, 0.19 mmol) in ethanol (2 mL) was heated at reflux for 4 hours. After cooling to room temperature, the solid product was collected by vacuum filtration to yield 3-pyridinecarboxaldehyde(6-(3-thienyl)thieno[3,2-d]pyrimidin-4-yl)hydrazone (40 mg, 87% yield) as a yellow solid.

출처