반응 #220490
ord-bf0296674c8a4d2b99889b4a6245a2a7
반응 방정식
iso-butanol
pyridine
2-bromopropionyl bromide
→
title compound
Iso-butyl 2-bromopropionate
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1세척washed with 1N HCl, water, aqueous NaHCO3, brine
- 2건조dried over magnesium sulfate or sodium sulfate
- 3기타Removal of the solvents at reduced pressure
실험 절차
To a mixture of iso-butanol and 1.0 equivalent of pyridine in dry diethyl ether was added dropwise 1.3 equivalents of 2-bromopropionyl bromide at 0° C. After stirring at room temperature for 16 hours, the reaction was diluted with diethyl ether, washed with 1N HCl, water, aqueous NaHCO3, brine and dried over magnesium sulfate or sodium sulfate. Removal of the solvents at reduced pressure gave the title compound as a clear oil.