반응 #220419

반응 방정식

N-(3,5-difluorophenylacetyl)-L-alanine

N-(3,5-Difluorophenylacetyl)-L-alanine

3-amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

→

title compound

3-(N′-(3,5-Difluorophenylacetyl)-L-alaninyl)amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

반응 조건

후처리

1. 1
   기타The reaction was monitored by tlc on silica gel (Rf=0.15 in 12% methanol/dichloromethane) and purification

실험 절차

Following General Procedure A above using N-(3,5-difluorophenylacetyl)-L-alanine (Example B) and 3-amino-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one (General Procedure 6-B), the title compound was prepared. The reaction was monitored by tlc on silica gel (Rf=0.15 in 12% methanol/dichloromethane) and purification was by flash chromatography using 12% methanol/dichloromethane as the eluant.

출처