반응 #2200591

ord-1fff50506c2a4a5d944f955940948bea

반응 방정식

O=C(O)C(=O)Cc1ccccc1
phenylpyruvic acid
CC(=O)C(=O)O
pyruvic acid
O=C(O)C(=O)CC(O)(Cc1ccccc1)C(=O)O
4-phenylmethyl-4-hydroxy-2-oxoglutaric acid

시약

없음

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

According to the study by the present inventors, it has been found that PtALD can catalyze the aldol condensation reaction of indolepyruvic acid with pyruvic acid (or oxalacetic acid) to yield 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid (IHOG), and the reaction of phenylpyruvic acid with pyruvic acid to yield 4-phenylmethyl-4-hydroxy-2-oxoglutaric acid (PHOG).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07432100B2uspto-grants-2008_10