반응 #2200590

ord-7a3e402a4a8b4604936da49f3e7c46ea

반응 방정식

O=C(O)C(=O)Cc1cc2ccccc2[nH]1
indolepyruvic acid
CC(=O)C(=O)O
pyruvic acid
O=C(O)CC(=O)C(=O)O
oxalacetic acid
O=C(O)C(=O)CC(O)(Cc1c[nH]c2ccccc12)C(=O)O
4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

According to the study by the present inventors, it has been found that PtALD can catalyze the aldol condensation reaction of indolepyruvic acid with pyruvic acid (or oxalacetic acid) to yield 4-(indol-3-ylmethyl)-4-hydroxy-2-oxoglutaric acid (IHOG), and the reaction of phenylpyruvic acid with pyruvic acid to yield 4-phenylmethyl-4-hydroxy-2-oxoglutaric acid (PHOG).

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07432100B2uspto-grants-2008_10