반응 #219767

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5-fluoro-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one

N-{4-methoxy-2-[(2S)oxiranylmethoxy]phenyl}acetamide

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title compound

N-[2-({(2S)-3-[4-(5-Fluoro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)-1-piperidinyl]-2-hydroxypropyl}oxy)-4-methoxyphenyl]acetamide

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후처리

1. 1
   기타The product was purified by preparative HPLC (Kromasil column; eluent: acetonitrile/water)

실험 절차

The title compound was prepared according to the procedure described in Example 30 above from 5-fluoro-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one and N-{4-methoxy-2-[(2S)oxiranylmethoxy]phenyl}acetamide. The product was purified by preparative HPLC (Kromasil column; eluent: acetonitrile/water) to afford a colourless solid (84%).

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