반응 #2195473

반응 방정식

phenol

sodium hydride

HCl

→

Dibenzofuran

용매

DMSO

반응 조건

후처리

1. 1
   추출The aqueous phase is extracted with MTB ether
2. 2
   건조The organic phase is dried over sodium sulfate
3. 3
   기타evaporated
4. 4
   기타chromatographed on silica gel

실험 절차

The phenol 10 is dissolved in DMSO under nitrogen, a 60% sodium hydride/mineral oil suspension is added, and the mixture is warmed to 120° C. After 5 hours at this temperature, the cooled batch is added to dil. HCl solution. The aqueous phase is extracted with MTB ether. The organic phase is dried over sodium sulfate, evaporated and chromatographed on silica gel.

출처