반응 #2190791

반응 방정식

(2-bromo-ethyl)-cyclopentane

triphenyl-phosphine

→

product

수율 83.2%

(2-Cyclopentyl-ethyl)-triphenyl-phosphonium bromide

수율 83.2%

용매

toluene

반응 조건

후처리

1. 1
   기타was prepared
2. 2
   온도Cool the reaction mixture to r.t.
3. 3
   농축concentrate
4. 4
   기타crystallize the product from diethylether

실험 절차

Dissolve (2-bromo-ethyl)-cyclopentane (15.25 g, 86.1 mmol) which was prepared according to Chem. Pharm. Bull. 1992, 40, 9, 2391-2398 in toluene, add triphenyl-phosphine (22.58 g, 86.1 mmol) and stir at 110° C. for 48 h. Cool the reaction mixture to r.t., concentrate and crystallize the product from diethylether to give 31.47 g product. MS (m/e): 359.0 (M+H).

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