반응 #219039
ord-0ccfe2a3f7d24f3ea57f2c641991f458
반응 방정식
(4-aminophenyl)acetic acid ethyl ester
cyclopentanecarbonitrile
(4-amino-3-cyclopentanecarbonylphenyl)acetic acid ethyl ester
2-aminothiazole
→
(4-Amino-3-cyclopentanecarbonylphenyl)acetic acid ethyl ester
[3-Cyclopentanecarbonyl-4-(3-thiazol-2-yl-ureido)phenyl]acetic acid ethyl ester
반응물
시약
없음
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
(4-Amino-3-cyclopentanecarbonylphenyl)acetic acid ethyl ester (2.7 g) is prepared from (4-aminophenyl)acetic acid ethyl ester (18.0 g, 0.1 mol) and cyclopentanecarbonitrile (9.5 g, 0.1 mol) following the general procedure I. [3-Cyclopentanecarbonyl-4-(3-thiazol-2-yl-ureido)phenyl]acetic acid ethyl ester (140 mg) is prepared from (4-amino-3-cyclopentanecarbonylphenyl)acetic acid ethyl ester (138 mg, 0.5 mmol) and 2-aminothiazole (0.060 g, 0.6 mmol) following the general procedure D.