반응 #2190171

반응 방정식

water

benzyl bromide

K2CO3

→

4-benzyloxy-2,3-dimethyl-phenol

용매

DMF

반응 조건

후처리

1. 1
   추출extracted with EtOAc
2. 2
   세척The EtOAc was washed with water
3. 3
   기타dried
4. 4
   기타evaporated
5. 5
   기타The residue was purified by silica gel column
6. 6
   세척eluting with 10% EtOAc in hexane

실험 절차

A mixture of 2,3-dimethyl-1,4-dihydroquinone (5 g) and benzyl bromide (6.2 g) and K2CO3 (10 g) in DMF (50 mL) was stirred at 120° C. for 5 h. The mixture was poured into water and extracted with EtOAc. The EtOAc was washed with water, dried and evaporated. The residue was purified by silica gel column eluting with 10% EtOAc in hexane to give 3.2 g of 4-benzyloxy-2,3-dimethyl-phenol as a pale solid.

출처