반응 #218959

반응 방정식

2-octanol

p-toluenesulfonic acid monohydrate

phenothiazine

→

product

2-octyl acrylate

용매

toluene

반응 조건

후처리

1. 1
   온도was heated to reflux
2. 2
   기타Water was separated from the toluene/water
3. 3
   workup.DISTILLATIONa Dean Stark distillation trap
4. 4
   온도After six hours at reflux a total of 37 milliliters of water
5. 5
   기타was collected in the trap
6. 6
   세척The reaction mixture was washed with 1 Molar aqueous sodium hydroxide (200 milliliters)
7. 7
   농축concentrated under reduced pressure
8. 8
   workup.DISTILLATIONThe remaining oil was distilled under reduced pressure (65-67° C. at 2 mmHg)

실험 절차

A mixture of 2-octanol (268.51 grams, 2.1 mol), AA (183.75 grams, 2.6 mol), p-toluenesulfonic acid monohydrate (5.00 grams, 26 mmol), toluene (250 grams) and phenothiazine (1.0 grams) was heated to reflux. Water was separated from the toluene/water azeotrope using a Dean Stark distillation trap. After six hours at reflux a total of 37 milliliters of water was collected in the trap. The reaction mixture was washed with 1 Molar aqueous sodium hydroxide (200 milliliters), then concentrated under reduced pressure. The remaining oil was distilled under reduced pressure (65-67° C. at 2 mmHg) to give the product as a colorless oil. (Yield: 248.6 grams)

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