반응 #2186817

ord-fd826f308ef948e6a1cddb7bbafcf949

반응 조건

상세 조건
See reaction.notes.procedure_details.

실험 절차

The methyl ester from Step I (565 mg, 1.13 mmol) was acylated with trans-4-methylcyclohexyl carboxylic acid chloride as previously described (example 11, step II) to give 41 mg (27%) of 5-cyclohex-1-enyl-3-[(trans-4-methyl-cyclohexanecarbonyl)-phenyl-amino]-thiophene-2-carboxylic acid methyl ester.

출처

DOI: 10.6084/m9.figshare.5104873.v1특허: US07569600B2uspto-grants-2009_08