반응 #2186175

반응 방정식

benzoyl chloride

sorbitol

→

Sorbitol Hexabenzoate

수율 74.0%

용매

triethylamine

반응 조건

후처리

1. 1
   workup.STIRRINGthe resulting mixture was stirred for an additional 30 minutes
2. 2
   기타After completion of the reaction
3. 3
   기타was lowered to room temperature
4. 4
   기타the resulting precipitates
5. 5
   여과were collected by filtration
6. 6
   세척Thereafter, washing
7. 7
   workup.ADDITIONby adding ethyl acetate-pure water
8. 8
   기타Subsequently, the organic phase was collected
9. 9
   workup.DISTILLATIONethyl acetate was distilled out under vacuum, whereby 100 parts by weight (at a yield of 74 percent) of white crystals
10. 10
    기타were obtained

실험 절차

While stirring, 71 parts by weight of benzoyl chloride were dripped over 30 minutes into a mixed solution of 30 parts by weight of sorbitol and 101 parts by weight of triethylamine maintained at 100° C., and the resulting mixture was stirred for an additional 30 minutes. After completion of the reaction, the temperature was lowered to room temperature, and the resulting precipitates were collected by filtration. Thereafter, washing was performed by adding ethyl acetate-pure water. Subsequently, the organic phase was collected and ethyl acetate was distilled out under vacuum, whereby 100 parts by weight (at a yield of 74 percent) of white crystals were obtained. The molecular weight of the resulting compound was 809.

출처