반응 #2183

반응 방정식

2-bromo-p-chloroacetophenone

methoxythiocarbonylhydrazine

→

5-(4-chlorophenyl)-3H,6H-1,3,4-thiadiazin-2-one

수율 48.4%

용매

acetonitrile

반응 조건

후처리

1. 1
   온도was refluxed overnight
2. 2
   온도cooled
3. 3
   여과filtered
4. 4
   세척The light yellow solid was washed with hexane
5. 5
   기타dried

실험 절차

A mixture of 2-bromo-p-chloroacetophenone (9.16 g), methoxythiocarbonylhydrazine (13.0 g) and acetonitrile (75 ml) was refluxed overnight and then cooled and filtered. The light yellow solid was washed with hexane and dried yielding 5-(4-chlorophenyl)-3H,6H-1,3,4-thiadiazin-2-one (4.3 g).

출처