반응 #218282

반응 방정식

phenothiazine

acetyl chloride

→

beige solid

10-acetyl-10H-phenothiazine

용매

toluene

반응 조건

후처리

1. 1
   workup.ADDITIONare added to a 500 ml flask
2. 2
   농축After concentration to dryness
3. 3
   여과filtered
4. 4
   기타After drying

실험 절차

20 g (0.1 mol) of phenothiazine followed by 14.3 ml (2 eq.) of acetyl chloride are added to a 500 ml flask containing 200 ml of toluene. The heterogeneous reaction mixture is stirred for 1 hour at 50° C. After concentration to dryness, the precipitate is taken up in a minimum of isopentane and filtered. After drying, 24 g of a beige solid is obtained with a quantitative yield. Melting point: 210-211° C.

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