반응 #2180220

반응 방정식

N-(4-Isopropylphenyl)acetamide

N-(4-isopropylphenyl)acetamide

nitric acid

H2SO4

→

N-(4-isopropyl-2-nitrophenyl)acetamide

반응 조건

후처리

1. 1
   기타at 0 to 5° C.
2. 2
   기타for 2 hrs
3. 3
   기타After the completion of the reaction, reaction mixture
4. 4
   workup.ADDITIONwas added to ice and pH
5. 5
   추출extracted with dichloromethane, which
6. 6
   기타was evaporated to dryness

실험 절차

N-(4-Isopropylphenyl)acetamide obtained in step I above was nitrated using nitric acid (1.2 eq)+H2SO4 (1.0 eq) at 0 to 5° C. for 2 hrs. After the completion of the reaction, reaction mixture was added to ice and pH was adjusted to 8, extracted with dichloromethane, which was evaporated to dryness to obtain N-(4-isopropyl-2-nitrophenyl)acetamide.

출처