반응 #217507

반응 방정식

4,6-dimethoxy-anthranilic acid

triethylorthoformate

→

5,7-dimethoxy-3,1-benzoxazine-4-one

수율 76.2%

반응 조건

후처리

1. 1
   기타The volatiles were evaporated under reduced pressure

실험 절차

A mixture of 1.0 g (5.07 mmol) of 4,6-dimethoxy-anthranilic acid, as prepared in Example 3, and 15 ml of triethylorthoformate (90.2 mmol) was heated to 140° C. for 4 h. The volatiles were evaporated under reduced pressure to give 0.8 g of 5,7-dimethoxy-3,1-benzoxazine-4-one as a yellow solid (76% yield), which was used without any further purification.

출처