반응 #217192

반응 방정식

Cn1cnc(C#N)c1

Fc1ccccc1Br

→

Cn1cnc(C#N)c1-c1cccc

수율 50.3%

CC(C)(C)c1ccc(-c2ccc

용매

CC(=O)N(C)C

반응 조건

후처리

1. 1
   workup.ADDITIONThe plate was removed from the glovebox, opened, and diluted to a 900 uL total volume with N,N-dimethylacetamide. The plate was stirred for 5 min and a 75 uL sample was taken and filtered into an HPLC analysis plate. The filter was rinsed with 400 uL acetonitrile/water (4:1) solution and analyzed by UHPLCMS
2. 2
   workup.STIRRING
3. 3
   workup.ALIQUOT
4. 4
   여과

출처