반응 #216906

반응 방정식

Pyridine-4-carbaldehyde

L-cysteine

charcoal

→

2-(4-pyridyl)-thiazolidine-4-carboxylic acid

수율 57.1%

용매

ethanol

반응 조건

후처리

1. 1
   온도was warm
2. 2
   여과The mixture was filtered
3. 3
   온도After cooling
4. 4
   여과the resultant crystalline precipitate was collected by filtration
5. 5
   세척washed with ethanol

실험 절차

Pyridine-4-carbaldehyde (1.07 g) and 1.21 g of L-cysteine were heated in 60% ethanol at a refluxing temperature for 4 hours. Activated charcoal (100 mg) was added to the reaction mixture while it was warm. The mixture was filtered. After cooling, the resultant crystalline precipitate was collected by filtration and washed with ethanol to give 1.2 g of 2-(4-pyridyl)-thiazolidine-4-carboxylic acid. Melting point 171°-173° C.

출처