반응 #216556

반응 방정식

H2O

1-bromo-3,3-dimethyl-2-butanone

sodium p-toluenesulfinate

→

1-(p-toluenesulfonyl)-3,3-dimethyl-2-butanone

수율 86.1%

용매

dimethylsulfoxide

반응 조건

후처리

1. 1
   기타reacted
2. 2
   여과The precipitate was filtered
3. 3
   세척washed with H2O
4. 4
   기타dried

실험 절차

To a solution of 1-bromo-3,3-dimethyl-2-butanone (33.3 g, 0.19 mole) in dimethylsulfoxide (330 ml), sodium p-toluenesulfinate (34.9 g, 0.20 mole) was added at 30°-40° C., and reacted with stirring at 60°-70° C. for 18 hours. The reaction mixture was poured into cold H2O (2 liter). The precipitate was filtered, washed with H2O and dried to afford 41.6 g of 1-(p-toluenesulfonyl)-3,3-dimethyl-2-butanone as white crystals. m.p. 119°-122° C.

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