반응 #216076

반응 방정식

Octadecylamine

Glycidol

→

white solid

수율 95.9%

3-Octadecylamino-1,2-Dihydroxy-Propane

수율 95.9%

용매

methanol

반응 조건

후처리

1. 1
   온도under reflux for one additional hour
2. 2
   온도cooled to room temperature
3. 3
   기타evaporated to dryness

실험 절차

Octadecylamine (18 g) was dissolved in 200 ml methanol and heated to 60° C. Glycidol (4.95 g) was added dropwise under constant stirring over one and half hours. The reaction mixture was kept under reflux for one additional hour, and then cooled to room temperature, and evaporated to dryness, resulting in 22 g white solid material. This was then recrystallized from hexane, to yield ODP, mp 81°-83° C.

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