반응 #215919

반응 방정식

3,5-di-t-butyl-4-hydroxybenzaldehyde

hydantoin

acetic acid

→

product

수율 50.6%

5-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]2,4-imidazolidinedione

수율 50.6%

용매

water

반응 조건

후처리

1. 1
   온도heated to reflux
2. 2
   여과the precipitate is filtered off
3. 3
   세척rinsed with water three times
4. 4
   기타dried
5. 5
   기타Recrystallization from acetonitrile

실험 절차

A mixture of 3,5-di-t-butyl-4-hydroxybenzaldehyde (7.0 g, 30 mmoles), hydantoin (3.0 g, 30 mmoles), μ-alanine (1.4 g, 16 mmoles), and acetic acid (40 ml) is stirred under an inert atmosphere and heated to reflux. After 48 hours the mixture is stirred into water (300 ml), and the precipitate is filtered off, rinsed with water three times, and dried. Recrystallization from acetonitrile gave the pure product (4.8 g), mp 251°-252° C.

출처