반응 #215693
ord-76ffd24e304642158af2cc014d8e9207
반응 방정식
4-bromophenylacetic acid
6-bromo-2-tetralone
Oxalyl chloride
→
4-bromo-phenylacetyl chloride
반응 조건
상세 조건
See reaction.notes.procedure_details.
실험 절차
The synthesis of 6-bromo-2-tetralone is accomplished by dissolving 4-bromophenylacetic acid in methylene chloride and dimethyl formamide, under nitrogen. Oxalyl chloride is added and the mixture is stirred under a positive nitrogen atmosphere to produce the 4-bromo-phenylacetyl chloride, at a yield which typically is better than 99%.