반응 #215141

반응 방정식

3-sulfamoyl-4-chlorobenzoyl chloride

1-phenyl-1-n-propylhydrazine

sodium bicarbonate

isopropanol

→

1-n-Propyl-1-phenyl-2-(3-sulfamoyl-4 chlorobenzoyl) hydrazine

용매

water

반응 조건

후처리

1. 1
   온도was chilled to 0°-5° C.
2. 2
   기타was collected
3. 3
   기타recrystallized from acetone/water, mp. 102° C. (d)

실험 절차

A vigorously stirred mixture of 14.0 g (0.1 mol) 1-phenyl-1-n-propylhydrazine, 8.4 g (0.1 mol) sodium bicarbonate, and 100 ml isopropanol was chilled to 0°-5° C., 23 g (0.09 mol) 3-sulfamoyl-4-chlorobenzoyl chloride was added in one portion, and the reaction mixture was allowed to stir for several hours, gradually warming to room temperature. Dilution with water and refrigeration overnight yielded solid material which was collected and recrystallized from acetone/water, mp. 102° C. (d).

출처