반응 #214850

반응 방정식

1-methylhydantoin

potassium carbonate

2-chloroethyl vinyl ether

dimethylformamide

→

1-Methyl-3-(2-vinyloxyethyl)-hydantoin

용매

toluene

반응 조건

후처리

1. 1
   기타is reacted for 2 hours and 30 minutes at 130°-138° C.
2. 2
   기타whilst removing
3. 3
   기타the water of reaction
4. 4
   기타are obtained
5. 5
   workup.DISTILLATIONThe crude product is distilled (boiling point 133° C.-134° C./0.2 mm Hg) and 108.5 g (81.8% of theory) of a colourless, viscous distillate
6. 6
   기타are obtained
7. 7
   기타this crystallises

실험 절차

A mixture of 82.6 g (0.72 mol) of 1-methylhydantoin, 50.7 g (0.37 mol) of anhydrous potassium carbonate, 89.6 g (0.84 mol) of 2-chloroethyl vinyl ether, 700 ml of dimethylformamide and 100 ml of toluene is reacted for 2 hours and 30 minutes at 130°-138° C., whilst removing the water of reaction. The mixture is then worked up as described in Example 1, and 128.5 g of a clear, reddish brown, viscous crude product (96.9% of theory) are obtained. The crude product is distilled (boiling point 133° C.-134° C./0.2 mm Hg) and 108.5 g (81.8% of theory) of a colourless, viscous distillate are obtained; this crystallises and melts at 54°-56° C.

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