반응 #2146678

반응 방정식

4-Acetylpyridine

p-toluene sulfonic acid methyl ester

→

4-acetyl-1-methylpyridinium p-toluene sulfonate

용매

ethanol

반응 조건

후처리

1. 1
   온도under reflux for 5 hours
2. 2
   기타The solvent was removed under vacuum in a rotary evaporator
3. 3
   기타After separating off the ether phase
4. 4
   기타the product slowly crystallized out
5. 5
   기타The product was dried under vacuum

실험 절차

4-Acetylpyridine (30.0 g, 0.25 mol) and p-toluene sulfonic acid methyl ester (55.8 g, 0.30 mol) in 500 ml ethanol were heated under reflux for 5 hours. The solvent was removed under vacuum in a rotary evaporator and the residue was taken up in ether. After separating off the ether phase, the product slowly crystallized out. The product was dried under vacuum. Yield: 59.9 g (82.5%);

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