반응 #214481
ord-53f6f81270b145c990fcf2571f79ce83
반응 방정식
반응 조건
상세 조건
See reaction.notes.procedure_details.
후처리
- 1기타collect the precipitate
- 2기타Collect the dry ethyl 6-bromo-5-chloro-3-(2-fluorophenyl)indole-2-carboxylate, m.p. 193°-194°
실험 절차
Add 1.0 ml of bromine to 4.6 g of ethyl 5-chloro-3-(2-fluorophenyl)indole-2-carboxylate in 250 ml of glacial acetic acid. Stir for 16 hours at room temperature, add water and collect the precipitate. Ws the precipitate with warm methanol. Collect the dry ethyl 6-bromo-5-chloro-3-(2-fluorophenyl)indole-2-carboxylate, m.p. 193°-194°.