반응 #214145

반응 방정식

1,4-dihydroxy-N-n-hexadecyl-2-naphthamide

methylsulfonylethanol

p-toluenesulfonic acid

toluene

→

( 2 )

1-Hydroxy-4-(β-methylsulfonylethoxy)-N-n-hexadecyl-2-naphthamide

용매

water

반응 조건

후처리

1. 1
   온도The mixture was refluxed
2. 2
   온도with heating for 5 hours
3. 3
   기타was removed
4. 4
   기타Toluene was removed under reduced pressure
5. 5
   workup.ADDITION100 ml of methanol was added to the mixture
6. 6
   여과The crystals thus deposited were collected by filtration

실험 절차

10 g (0.023 mol) of 1,4-dihydroxy-N-n-hexadecyl-2-naphthamide, 5.7 g (0.046 mol) of methylsulfonylethanol and 4.4 g (0.023 mol) of p-toluenesulfonic acid were added to 50 ml of dehydrated toluene. The mixture was refluxed with heating for 5 hours and the water produced was removed. Toluene was removed under reduced pressure. 100 ml of methanol was added to the mixture. The crystals thus deposited were collected by filtration to obtain 10.8 g (88%) of Coupler (2). Melting Point: 107° to 109° C. (recrystallized from methanol).

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