반응 #2139931

반응 방정식

9-ethyl-3-carbazolecarboxaldehyde

hydrazine monohydrate

triethylamine

→

9-Ethyl-3-carbazolecarboxaldehyde hydrazone

용매

tetrahydrofuran

water

반응 조건

후처리

1. 1
   기타equipped with a mechanical stirrer and an addition funnel
2. 2
   workup.STIRRINGthe reaction mixture was stirred at room temperature for 2 hours
3. 3
   여과A precipitate was collected by filtration
4. 4
   세척washed repeatedly with water
5. 5
   기타to give crude, i.e.
6. 6
   기타without further purification, 9-ethyl-3-carbazolecarboxaldehyde hydrazone, which

실험 절차

A quantity of 98% hydrazine monohydrate (50 ml, 1.4 mole, obtained from Aldrich, Milwaukee, Wis.) and 10 ml of triethylamine (obtained from Aldrich, Milwaukee, Wis.) were added to a 250 ml, 2-neck round bottom flask equipped with a mechanical stirrer and an addition funnel. The solution was stirred vigorously at room temperature for a period of 10-15 min. A solution of 9-ethyl-3-carbazolecarboxaldehyde (22.3 g, 0.1 mol, from Aldrich, Milwaukee, Wis.) in 30 ml of tetrahydrofuran (THF) was added slowly to the round bottom flask. After the addition of aldehyde was completed, the reaction mixture was stirred at room temperature for 2 hours. Then, the reaction mixture was diluted with 50 ml of water. A precipitate was collected by filtration and washed repeatedly with water to give crude, i.e. without further purification, 9-ethyl-3-carbazolecarboxaldehyde hydrazone, which was used immediately in the next step.

출처