반응 #2125481

반응 방정식

1-azabicyclo[2.2.2]oct -4-yl(diphenyl)methanol

3-bromopropyl 4-fluorophenyl ether

→

desired product

수율 43.7%

1-{3-[(4-fluorophenyl)oxy]propyl}-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octane bromide

수율 43.7%

용매

CH3CN

반응 조건

후처리

1. 1
   기타were reacted

실험 절차

Following the general procedure outlined in Example 3, 1-azabicyclo[2.2.2]oct -4-yl(diphenyl)methanol (0.0182 g, 0.0621 mmol) and 3-bromopropyl 4-fluorophenyl ether (0.0173 g, 0.0742 mmol) in 2 CH3CN/3CHCl3 (4.0 mL) were reacted to give the desired product (0.0143 g, 43.7%). ELMS m/z 446(M+) Rt (1.96 min).

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