반응 #2116

반응 방정식

benzylethyl 4-(7-ethoxymethyl-3-methylxanthin-1-yl)-butylphosphonate

ammonia

→

Monoethyl ammonium [4-(7-ethoxymethyl-3-methylxanthin-1-yl)butyl]-phosphonate

용매

ethanol

반응 조건

후처리

1. 1
   여과The catalyst was filtered off
2. 2
   농축the filtrate was concentrated under reduced pressure
3. 3
   기타the solution obtained
4. 4
   기타after evaporating the solvent
5. 5
   기타was then crystallized from diisopropyl ether

실험 절차

6.3 g (0.013 mol) of benzylethyl 4-(7-ethoxymethyl-3-methylxanthin-1-yl)-butylphosphonate were hydrogenated in 100 ml of ethanol over 0.5 g of palladium (10%) on active carbon at room temperature in the course of 4 hours. The catalyst was filtered off, the filtrate was concentrated under reduced pressure, the solution obtained was treated with methanolic ammonia and the residue which remained after evaporating the solvent was then crystallized from diisopropyl ether.

출처